SAB5700342

Anti-Phospho-Camk2a-T286 antibody produced in rabbit

• Sinónimos: CAMK2A, CAMKA
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 22; 54
• species reactivity: human, mouse, rat
• concentration: 0.8 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q9UQM7
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr286)
• Gene Information: human ... Camk2a(815)

Descripción

General description

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding T286 of human Camk2a

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable