SAB4502360

Anti-PKC δ antibody produced in rabbit

affinity isolated antibody

• Sinónimos: KPCD, PKC-δ, PRKCD, kinase PKC-δ, nPKC-δ
• MDL number: MFCD00162772
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 77 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: Q05655
• UniProt accession no.: Q05655
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PRKCD(5580)

Descripción

General description

Anti-PKC δ antibody detects endogenous levels of total PKC δ protein.

The PKC δ (protein kinase C δ) gene is mapped to human chromosome 3p21.1. It is predominantly expressed in the heart.

Immunogen

The antiserum was produced against synthesized peptide derived from human PKC delta.

Immunogen Range: 471-520

Biochem/physiol Actions

The PKC (protein kinase C) protein is known to mediate different cellular processes such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. PKC is also associated with learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC δ (protein kinase C δ) regulates neutrophil migration during sepsis. PKC δ has anticancer effect by reducing the cell proliferation rate and also stimulating apoptosis by arresting cell cycle. PKC δ induces neuron proliferation and survival, thereby it is associated with memory.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable