SAB4500465

Anti-CRHR1 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CRF-R, CRF1, CRH-R 1, Corticotropin-releasing factor receptor 1, Corticotropin-releasing hormone receptor 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 50 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI accession no.: P34998
• UniProt accession no.: P34998
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CRHR1(1394)

Descripción

General description

Anti-CRHR1 Antibody detects endogenous levels of total CRHR1 protein.

CRHR1 (corticotropin releasing factor receptor 1) is a member of the G-protein-coupled receptor superfamily of brain-gut neuropeptides. It is highly expressed in the amygdala, hippocampus and frontal cortex. It has 13 exons and located on human chromosome 17q12-q22.

Immunogen

The antiserum was produced against synthesized peptide derived from human CRHR1.

Immunogen Range: 75-124

Application

Anti-CRHR1 antibody has been used in immunoprecipitation and western blotting.

Biochem/physiol Actions

CRHR1 (corticotropin releasing factor receptor 1) blocks the multiplication of endocrine-related cancer cell lines. It helps to initiate signal transduction pathways, that controls various functions like stress, reproduction, immune response and obesity.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable