SAB4301075

Anti-DGAT1 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: ARAT, ARGP1, DGAT
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 55 kDa
• species reactivity: rat, mouse, human
• concentration: 2.8 mg/mL
• technique(s): immunohistochemistry: 1:50- 1:200; western blot: 1:500-1:2000 (Cell Lysate)
• isotype: IgG
• accession no.: NP_036211.2
• UniProt accession no.: O75907
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... DGAT1(8694)

Descripción

General description

Diacylglycerol-acyltransferase 1 (DGAT1), a transmembrane protein, is a member of the membrane-bound O-acyltransferase superfamily. It is seen in the endoplasmic reticulum of several cells. DGAT1 is ubiquitously expressed in humans. A high level of mRNA is seen in the small intestine. It has three transmembrane domains. The DGAT1 gene is mapped to human chromosome 8q24.3.

Specificity

The antibody detects endogenous levels of total DGAT1 protein.

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human diacylglycerol O-acyltransferase 1

Application

Anti-DGAT1 antibody produced in rabbit has been used in immunoblotting.

Biochem/physiol Actions

Diacylglycerol-acyltransferase 1 (DGAT1) converts diacylglycerol and fatty acyl-CoA to triacylglycerol. It participates in energy storage. DGAT1 plays a key role in cancer progression. Activity of DGAT1 is essential for the physiologic absorption of vitamin D. Absence of DGAT1 activity is linked with body weight and adiposity reduction, and increased insulin sensitivity. Aberrations in the DGAT1 gene are associated with congenital diarrheal disorder (CDD).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable