SAB4200068

Anti-PSPC1 (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Sinónimos: Anti-PSP1, Anti-Paraspeckle protein 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~59 kDa
• species reactivity: human
• enhanced validation: independent; Learn more about Antibody Enhanced Validation
• concentration: ~1.0 mg/mL
• technique(s): indirect immunofluorescence: 1.2-2.5 μg/mL using paraformaldehyde fixed HEK-293T cells; western blot (chemiluminescent): 0.5-1 μg/mL using lysates of HEK-293T cells
• UniProt accession no.: Q8WXF1
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PSPC1(55269)

Descripción

General description

Paraspeckle protein 1 (PSP1/ PSPC1) has two isoforms, α and β. PSPC1 belongs to the Drosophila melanogaster behavior, human splicing (DBHS) protein family.

Application

Anti-PSPC1 (N-terminal) antibody produced in rabbit may be used in several immunochemical techniques including immunoblotting (~59 kDa) and immunofluorescence. It has also been used in RNA immunoprecipitation (RIP) experiment.

Biochem/physiol Actions

Paraspeckle protein 1(PSP1/ PSPC1) is implicated in the regulation of nuclear receptors such as the progesterone receptor and the thyroid receptor, and in a wide range of processes such as transcription, splicing, and RNA metabolism. It acts as a marker for paraspeckles, which are ribonucleoprotein bodies found in the interchromatin space of mammalian cell nuclei that are often located adjacent to splicing speckles.

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable