SAB1300843

Anti-APPBP1 (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Sinónimos: Anti-A-116A10.1, Anti-HPP1, Anti-NAE1, Anti-Ula-1, NEDD8-activating enzyme E1 regulatory subunit
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI accession no.: NP_003896
• UniProt accession no.: Q13564
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... APPBP1(8883)

Descripción

General description

APPBP1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer′s disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPBP1 is required for cell cycle progression through the S/M checkpoint.

Immunogen

APPBP1 (NP_003896, 5-34)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human APPBP1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable