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Merck
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Key Documents

S9399

Sigma-Aldrich

Staphylococcal enterotoxin A from Staphylococcus aureus

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About This Item

Número de CAS:
642595-84-4
MDL number:
MFCD00082015
UNSPSC Code:
12352200

contains

sodium phosphate buffer as balance

Quality Level

200

composition

Protein, ~10% Lowry

availability

not available in USA

impurities

Staphylococcal enterotoxin B (SEB), essentially free

solubility

H2O: complete 1 mg/ml, clear, colorless

storage temp.

2-8°C

General description

Staphylococcal enterotoxin A belongs to the family of staphylococcal exotoxins. It is secreted by Staphylococcus aureus, a Gram-positive bacteria.

Application

Staphylococcal enterotoxin A from Staphylococcal aureus was injected peritoneally in mice to induce sepsis.10
Staphylococcal enterotoxin A from Staphylococcus aureus has been used as an external standard in for the verification of TRANSIA assay kit, RIDASCREEN assay kit and Vidas Set 2 method. For in vitro toxin stimulation of mouse splenocytes.

Biochem/physiol Actions

Staphylococcal enterotoxin A from Staphylococcus aureus is leading agent that causes of food poisoning. A concentration of as little as 0.5 mg/ml is sufficient to result in nausea, vomiting, diarrhea and cramps.8 It stimulates the cell proliferation of peripheral lymphocytes, induces the production of interferons and is important for gut immunity against S. aureus infections.9 It acts as a super antigen for T-lymphocytes.

Packaging

Package size based on protein content

related product

Referencia del producto
Descripción
Precios

08168

Timestrip Plus™ 8 °C

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hongshi Yu et al.
BMC genomics, 10, 416-416 (2009-09-08)
WNT4 is a critical signalling molecule in embryogenesis and homeostasis, but the elements that control its transcriptional regulation are largely unknown. This study uses comparative cross species sequence and functional analyses between humans and a marsupial (the tammar wallaby,Macropus eugenii)
Staphylococcal enterotoxin A (SEA).
L Spero et al.
Methods in enzymology, 78(Pt A), 331-336 (1981-01-01)
Targeting of key pathogenic factors from gram-positive bacteria by the soluble ectodomain of the scavenger-like lymphocyte receptor CD6
<BIG>Martinez F, et al.</BIG>
The Journal of Infectious Diseases, 209, 1077-1086 (2013)
Marcin Kłak et al.
Scandinavian journal of infectious diseases, 42(5), 351-358 (2010-01-27)
Haemostatic balance shifts towards pro-coagulation during infection. Plasminogen, a key molecule of fibrinolysis, may play an important role in the pathogenesis of staphylococcal infections. In the present study, we assessed the impact of inhibition of plasminogen activation by tranexamic acid
Staphylococcal Enterotoxins
<BIG>Pinchuk IV, et al.</BIG>
Toxins, 2, 2177-2177 (2010)
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