R3030

Risperidone

≥98% (HPLC), powder, antipsychotic

• Sinónimos: R 64,766
• Fórmula empírica (notación de Hill): C₂₃H₂₇FN₄O₂
• Número de CAS: 106266-06-2
• Peso molecular: 410.48
• MDL number: MFCD00274576
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824020
• NACRES: NA.77

Propiedades

• product name: Risperidone, ≥98% (HPLC), powder
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: ≥5 mg/mL
• originator: Johnson & Johnson
• storage temp.: room temp
• SMILES string: CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1
• InChI: 1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3
• InChI key: RAPZEAPATHNIPO-UHFFFAOYSA-N
• Gene Information: human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

Descripción

General description

Risperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D₂, histamine H₁ and α₁ and α₂ adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autism.

Application

Risperidone has been used:

• to study its effects on bone formation and differentiation
• to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients
• to reverse induced schizophrenia-like behavior in mice

Biochem/physiol Actions

Risperidone is an antipsychotic; serotonin-dopamine antagonist.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges