PZ0284

PF-04753299

≥98%

• Sinónimos: α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide, (+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, PF 04753299, PF-4753299
• Fórmula empírica (notación de Hill): C₁₈H₂₁NO₄S
• Número de CAS: 1289620-49-0
• Peso molecular: 347.43
• MDL number: MFCD22683864
• UNSPSC Code: 51111800
• PubChem Substance ID: 329823811
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98%
• form: powder
• color: white to light brown
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: room temp
• SMILES string: O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2
• InChI: 1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1
• InChI key: GDYIQUFNICPYHF-GOSISDBHSA-N

Descripción

Biochem/physiol Actions

PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable