PRS3331

Anti-XIAP antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-X-linked inhibitor of apoptosis
• MDL number: MFCD01633419
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: predicted mol wt 55 kDa
• species reactivity: mouse, human
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: P98170
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... XIAP(331)

Descripción

General description

XIAP (X-linked inhibitor of apoptosis protein) belongs to the inhibitor of apoptosis (IAP) family. It is located on chromosome Xq25.

Immunogen

a synthetic peptide corresponding to 13 amino acids at the C-terminus of human XIAP.

Application

Anti-XIAP has been used in immunohistochemistry {16,17}.

Biochem/physiol Actions

XIAP (X-linked inhibitor of apoptosis protein) modulates several cellular processes like TGF-β (transforming growth factor β) signaling, NF-κB (nuclear factor-κB) pathway, autophagy and inflammatory responses. XIAP mutations are associated with X-linked lymphoproliferative syndrome type 2 (XLP-2).

Linkage

The action of this antibody can be blocked using blocking peptide SBP3331.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable