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Merck
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Key Documents

PLA0112

Sigma-Aldrich

Rabbit anti-CtIP Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Sinónimos:

COM1, CTBP-interacting protein, CtIP, JWDS, RBBP-8, RIM, Retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like, SAE2, SCKL2, Seckel syndrome 2, retinoblastoma binding protein 8, sporulation in the absence of SPO11 protein 2 homolog

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

mouse, human

technique(s)

immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000

accession no.

NP_002885.1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... CtIP(5932)

Immunogen

The epitope recognized by PLA0112 maps to a region between residue 850 and the C-terminus (residue 897) of human CtBP Interacting Protein (Retinoblastoma Binding Protein 8) using the numbering given in entry NP_002885.1 (GeneID 5932).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

CtIP (CTBP interacting protein) was first identified as a protein that interacted with CTBP (C-terminus-binding protein of adenovirus E1A). CtIP has also been identified as a protein that interacts with the tumor suppressors pRb and BRCA1 and has been implicated as a tumor suppressor itself.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Bárbara Alcaraz Silva et al.
The Journal of biological chemistry, 289(33), 22771-22784 (2014-07-02)
Chromosome ends contain nucleoprotein structures known as telomeres. Damage to chromosome ends during interphase elicits a DNA damage response (DDR) resulting in cell cycle arrest. However, little is known regarding the signaling from damaged chromosome ends (designated here as "TIPs")

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