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Merck

P0930

Sigma-Aldrich

Polyvinylpyrrolidone

powder, BioXtra, suitable for mouse embryo cell culture

Sinónimos:

PVP, Polyvidone, Povidone

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About This Item

Fórmula lineal:
(C6H9NO)n
Número de CAS:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.75

product line

BioXtra

Quality Level

form

powder

technique(s)

cell culture | embryo: suitable

viscosity number

28-32(lit.)

solubility

H2O: 100 mg/mL

application(s)

agriculture

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

Polyvinylpyrrolidone (PVP)/polyvidone is used in cosmetics, medical and hair care products. Povidone iodine, a compound of polyvinylpyrrolidone and iodine can be used as an antiseptic and antibacterial agent. Dry form of PVP is available as a light flaky hygroscopic powder, which can absorb up to 40% of water by its weight.

Application

Polyvinylpyrrolidone has been used as a component in phosphate buffer saline (PBS) for immunostaining. It has also been used as a component in phosphate buffer saline (PBS) to wash parthenogenetic embryos for immunocytochemical analysis.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Antiseptic drugs and disinfectants
Side Effects of Drugs Annual: A world-wide yearly survey of new data and trends in adverse drug reactions., 28, 261-261 (2005)
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
Nichols J, et al.
Development, 136(19), 3215-3222 (2009)
Polymer synthesis and processing
Natural and Synthetic Biomedical Polymers, 1-31 (2014)
Cloned ferrets produced by somatic cell nuclear transfer
Li Z, et al.
Developmental Biology, 293, 439-448 (2006)
Bryan D James et al.
ACS biomaterials science & engineering, 6(6), 3673-3689 (2020-07-25)
Increasingly being recognized is the role of the complex microenvironment to regulate cell phenotype; however, the cell culture systems used to study these effects in vitro are lagging. The complex microenvironment is host to a combination of biological interactions, chemical

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