O1383
Ácido oleico
suitable for cell culture, BioReagent
Sinónimos:
Ácido cis-9-octadecenoico, Ácido elaínico
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About This Item
Fórmula lineal:
CH3(CH2)7CH=CH(CH2)7COOH
Número de CAS:
Peso molecular:
282.46
Beilstein/REAXYS Number:
1726542
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.75
Productos recomendados
biological source
palm oil
Quality Level
vapor pressure
1 mmHg ( 176 °C)
product line
BioReagent
assay
≥99% (GC)
form
viscous liquid
technique(s)
cell culture | mammalian: suitable
refractive index
n20/D 1.459 (lit.)
bp
194-195 °C/1.2 mmHg (lit.)
mp
13-14 °C (lit.)
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General description
Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is not an essential fatty acid (EFA); however, providing it to cells in culture reduces energy demand.
Oleic acid mediates complete oxidation of fatty acid in sirtuin1- proliferator-activated receptor γ coactivator−1α (SIRT1-PGC-1α) signalling pathway. Oleic acid shows anti-inflammatory properties related to atherosclerosis and insulin resistant state. Oleic acid inhibits permeability in gap junctions and promotes glucose uptake in astrocytes. Oleic acid aids in neural cell proliferation by increasing glucose uptake and by protein kinase C (PKC) activation. Oleic acid is essential for axonal growth and neuronal clustering.
Application
Oleic acid has been used:
- in fatty acid oxidation rate experiments in myotubes and in Sirt1 enzyme assay
- to determine quantitatively its effect on lipid droplets by optical diffraction tomography
- as a fatty acid source in the medium for primary hepatocyte culture
Packaging
Sealed ampule.
Caution
Unsaturated fatty acids are subject to oxidation and peroxidation. Consider complexed fatty acid supplements.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Artículos
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