N3139

ββ-Nicotinamida adenina dinucleótido fosfato hydrate

powder, BioReagent, suitable for cell culture

• Sinónimos: Nucleótido de trifosfopiridina sodium salt hydrate
• Fórmula empírica (notación de Hill): C₂₁H₂₇N₇NaO₁₇P₃ · xH₂O
• Número de CAS: 698999-85-8
• Peso molecular: 765.39 (anhydrous basis)
• MDL number: MFCD00150480
• UNSPSC Code: 12352205
• PubChem Substance ID: 24897624
• NACRES: NA.75

Propiedades

• product line: BioReagent
• Quality Level: 200
• assay: ≥98% (HPLC); ≥98% (spectrophotometric assay)
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 175-178 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• storage temp.: −20°C
• SMILES string: O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]
• InChI: 1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1
• InChI key: CYQLUFJYVTUUFN-WUEGHLCSSA-M

Descripción

Application

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate has been used in the purification and crystallization of CHORD–Sgt1 cytochrome b 5 reductases (CS–b5R). It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 medium for direct hepatic reprogramming using mouse embryonic fibroblasts (MEFs).

Biochem/physiol Actions

Aceptor de electrones

Nicotinamide adenine dinucleotide phosphate (NADP) is an indispensable cofactor that participates in cellular redox reactions. It acts as a hydride-accepting coenzyme and participates in substrate oxidation reactions during metabolism.

Packaging

Envasado por peso sólido.

Analysis Note

Meets or exceeds NRC specifications and is comparable to any commercial preparation available.

Other Notes

Esta es la forma común del NADP. No confundir con 3′−NADP o α-NADP.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable