K3000

Kinetin riboside

proapoptotic anitproliferative plant growth regulator

• Sinónimos: 6-Furfurylaminopurine riboside, N⁶-(2-Furanyl­methyl)adenosine, N⁶-Furfuryladenosine
• Fórmula empírica (notación de Hill): C₁₅H₁₇N₅O₅
• Número de CAS: 4338-47-0
• Peso molecular: 347.33
• EC Number: 224-389-3
• MDL number: MFCD00037987
• UNSPSC Code: 12352207
• PubChem Substance ID: 24896224
• NACRES: NA.72

Propiedades

• assay: ≥98% (HPLC); ≥98% (TLC)
• form: powder
• solubility: acetic acid: 49.00-51.00 mg/mL, clear, colorless to yellow
• storage temp.: 2-8°C
• SMILES string: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccco4)ncnc23
• InChI: 1S/C15H17N5O5/c21-5-9-11(22)12(23)15(25-9)20-7-19-10-13(17-6-18-14(10)20)16-4-8-2-1-3-24-8/h1-3,6-7,9,11-12,15,21-23H,4-5H2,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
• InChI key: CAGLGYNQQSIUGX-SDBHATRESA-N
• Gene Information: rat ... Adora1(29290) , Adora2a(25369) , Adora3(25370)

Descripción

General description

Kinetin riboside is a ribosylated form of kinetin. It is a natural cytokinin plant hormone.

Application

Kinetin riboside may be used:

• to study its cytotoxic effects on plant and animal tumor cells
• to investigate its apoptotic effects in both cancer and immortalized cells
• to elucidate its influence on human prostate cell epithelial-mesenchymal transition in vitro

Biochem/physiol Actions

Kinetin riboside exhibits cytotoxic and antiproliferative activities. In addition, it also shows anticancer activity by inducing apoptosis in various types of cancers including myeloid leukemia cells, mouse melanoma B16F-10 cells, and plant tumor cells.

Información de seguridad

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)