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Merck

G9003

Sigma-Aldrich

D-Glutamine

≥98% (HPLC)

Sinónimos:

D-2-Aminoglutaramic acid, D-Glutamic acid 5-amide

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About This Item

Fórmula empírica (notación de Hill):
C5H10N2O3
Número de CAS:
Peso molecular:
146.14
Beilstein/REAXYS Number:
1723796
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.32

product name

D-Glutamine, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

color

white

application(s)

cell analysis

SMILES string

N[C@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1

InChI key

ZDXPYRJPNDTMRX-GSVOUGTGSA-N

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General description

Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids.

Application

D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.

Biochem/physiol Actions

Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%.

Other Notes

Unnatural isomer of glutamine

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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