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Merck

FD70S

Sigma-Aldrich

Isotiocianato de fluoresceína-dextrano

average mol wt 60,000-76,000

Sinónimos:

FITC–Dextrano

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About This Item

Número de CAS:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

conjugate

FITC conjugate

form

powder

mol wt

average mol wt 60,000-76,000

extent of labeling

0.003-0.020 mol FITC per mol glucose

color

yellow to yellow-orange

solubility

H2O: 25 mg/mL, clear to slightly hazy, yellow-orange

storage temp.

2-8°C

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Application

Dextrano marcado con isotiocianato de fluoresceína para su posible uso en estudios de perfusión en animales.
FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. Small FITC-dextrans are also used to measure processes such as endocytosis and cell junction permeability. FITC-dextran 70 kDa (FD-70) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. FD-70 may be used in microvascular and cell monolayer permeability studies.

Linkage

Similar to FD-70, but produced by Sigma.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Ting Su et al.
International journal of pharmaceutics, 555, 291-302 (2018-11-25)
Polyphosphates are important polyanionic electrolytes that play a major role in stabilization and consolidation of colloids surface and interior microstructures. In this study, the polyelectrolyte complexes (PEC) microcapsules (sodium cellulose sulfate-chitosan hydrochloride, sample 1), and the patched ones via sodium
Gabriela Hurtado-Alvarado et al.
PloS one, 11(11), e0167236-e0167236 (2016-11-29)
Chronic sleep restriction induces blood-brain barrier disruption and increases pro-inflammatory mediators in rodents. Those inflammatory mediators may modulate the blood-brain barrier and constitute a link between sleep loss and blood-brain barrier physiology. We propose that adenosine action on its A2A
Michael J Shirey et al.
Journal of neurophysiology, 114(1), 309-322 (2015-05-15)
Changes in brain temperature can alter electrical properties of neurons and cause changes in behavior. However, it is not well understood how behaviors, like locomotion, or experimental manipulations, like anesthesia, alter brain temperature. We implanted thermocouples in sensorimotor cortex of
Rima Chattopadhyay et al.
Redox biology, 12, 438-455 (2017-03-21)
Resolvins are a novel class of lipid mediators that play an important role in the resolution of inflammation, although the underlying mechanisms are not very clear. To explore the anti-inflammatory mechanisms of resolvins, we have studied the effects of resolvin
Maira Carrillo et al.
Medicine, 97(39), e12392-e12392 (2018-10-04)
Imaging of placental tissues is a difficult task, because of specific for this organ complex multicellular and 3D tissue structure. The tissue clearing systems (X-CLARITY) system is a valuable tool for the examining the expression of molecular pathways in whole

Contenido relacionado

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

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