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Merck

D2631

Sigma-Aldrich

Dihexadecyl phosphate

Sinónimos:

DHP, Dicetyl phosphate

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About This Item

Fórmula lineal:
[CH3(CH2)15O]2P(O)OH
Número de CAS:
Peso molecular:
546.85
Beilstein/REAXYS Number:
1717117
EC Number:
MDL number:
UNSPSC Code:
51191904
PubChem Substance ID:
NACRES:
NA.25

description

anionic

Quality Level

form

powder

mol wt

546.85 g/mol

technique(s)

DNA extraction: suitable

mp

74-75 °C (lit.)

lipid type

phospholipids

storage temp.

−20°C

SMILES string

OP(OCCCCCCCCCCCCCCCC)(OCCCCCCCCCCCCCCCC)=O

InChI

1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)

InChI key

RNPXCFINMKSQPQ-UHFFFAOYSA-N

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Biochem/physiol Actions

Dihexadecyl phosphate (DHP) is a negatively charged lipid that is used for the formation of model membranes.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Hamdy Abdelkader et al.
Journal of pharmaceutical sciences, 100(5), 1833-1846 (2011-01-20)
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as
Haruyuki Ishii et al.
Colloids and surfaces. B, Biointerfaces, 92, 372-376 (2011-12-16)
Hollow silica particle was obtained with a vesicle template synthesis in water under ambient conditions in the presence of ammonia. Biomimetic vesicles, liposomes were used, which consisted of a zwitterionic phospholipid, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and a tiny amount of charged amphiphiles
Abbas Pardakhty et al.
International journal of pharmaceutics, 328(2), 130-141 (2006-09-26)
In this study, niosomes of polyoxyethylene alkyl ethers (Brij) were prepared for encapsulation of insulin by film hydration method. Without cholesterol, brij 35 and brij 58 did not form niosomes, apparently because of relatively large polar head groups in comparison
Laurent Salade et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 129, 257-266 (2018-06-15)
The nose-to-brain delivery of ghrelin loaded in liposomes is a promising approach for the management of cachexia. It could limit the plasmatic degradation of ghrelin and provide direct access to the brain, where ghrelin's specific receptors are located. Anionic liposomes
Mahmoud Mokhtar et al.
International journal of pharmaceutics, 361(1-2), 104-111 (2008-06-26)
Proniosomal gels or solutions of flurbiprofen were developed based on span 20 (Sp 20), span 40 (Sp 40), span 60 (Sp 60), and span 80 (Sp 80) without and with cholesterol. Nonionic surfactant vesicles (niosomes) formed immediately upon hydrating proniosomal

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