A9605

AC-93253

≥98% (HPLC)

• Sinónimos: 2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazolium iodide
• Fórmula empírica (notación de Hill): C₂₃H₂₅N₂SI
• Número de CAS: 108527-83-9
• Peso molecular: 488.43
• MDL number: MFCD03769029
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724406

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: dark purple
• solubility: DMSO: >10 mg/mL; H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: [I-].CC[n+]1c(\C=C\C=C2\N(C)c3ccccc3C2(C)C)sc4ccccc14
• InChI: 1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1
• InChI key: TWBRXRGFFUATNI-UHFFFAOYSA-M

Descripción

Biochem/physiol Actions

AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC₅₀ = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.

Features and Benefits

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable