94261

LL-37 (human) trifluoroacetate salt

≥95% (HPLC)

• Sinónimos: Human LL-37 amide Trifluoroacetate
• Fórmula empírica (notación de Hill): C₂₀₅H₃₄₁N₆₁O₅₂ · xC₂HF₃O₂
• Peso molecular: 4492.28 (free base basis)
• UNSPSC Code: 51101500
• NACRES: NA.85

Propiedades

• assay: ≥95% (HPLC)
• form: powder (Lyophilisate)
• color: colorless to white
• solubility: H₂O: 1 mg/mL, clear, colorless
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria; viruses
• mode of action: cell membrane | interferes
• storage temp.: −20°C

Descripción

Amino Acid Sequence

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH₂

General description

Chemical structure: peptide

Application

LL-37 is used to study host defense mechanisms.

Biochem/physiol Actions

LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria.

Packaging

1mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)