Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

75633

Sigma-Aldrich

Osmium tetroxide solution

suitable for electron microscopy, 2% in H2O

Sinónimos:

Osmium(IV) oxide

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula lineal:
OsO4
Número de CAS:
20816-12-0
Peso molecular:
254.23
MDL number:
MFCD00011150
UNSPSC Code:
12171500
PubChem Substance ID:
57652577
NACRES:
NA.47
grade:
for analytical purposes
form:
solution

grade

for analytical purposes

form

solution

reaction suitability

reagent type: oxidant

concentration

2% in H2O

technique(s)

electron microscopy: suitable

color

colorless to yellow

density

1.0 g/mL at 20 °C
1.0 g/mL at 20 °C

application(s)

hematology
histology

storage temp.

2-8°C

SMILES string

O=[Os](=O)(=O)=O

InChI

1S/4O.Os

InChI key

VUVGYHUDAICLFK-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

General description

Osmium tetroxide (OsO4) also referred to as osmium, is a heavy tetrahedral, symmetrical molecule. It is both a dye and a non-coagulant fixative agent in electron microscopy primarily used for the examination of biological tissue components in the histopathology laboratory. Specimens are postfixed with osmium tetroxide to ensure the preservation of the lipids.

Application

Osmium tetroxide solution has been used as a fixative in electron microscopy.

Biochem/physiol Actions

Osmium tetroxide is also referred to as osmium and is mainly used as a secondary fixative of tissues. The molecule reacts with lipid moieties and is responsible for the oxidation of unsaturated bonds of fatty acids. This reaction adds density and contrast to biological samples. In normal tissues, presence of osmium results in intense black staining which can be viewed by normal eye. In addition, it can be used as a mordant (a molecule which combines with stain or dye at later stages) in electron microscopy, thereby enhancing lead staining.

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
BCCK2370
BCCH6755
BCCF5871
BCCC6174
BCCB9800

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Regulation of nitric-oxide production in hemocytes of the ascidian Phallusia nigra.
de Barros CM, et al.
Nitric Oxide, 38, 26-26 (2014)
3-acetylpyridine-induced degeneration in the adult ascidian neural complex: Reactive and regenerative changes in glia and blood cells.
Medina BN, et al.
Developmental neurobiology, 75, 877-877 (2015)
Electron Microscopy: Principles and Techniques for Biologists (1999)
Carsten Købler et al.
Analytical and bioanalytical chemistry, 406(16), 3863-3873 (2014-01-23)
Ultrastructural characterisation is important for understanding carbon nanotube (CNT) toxicity and how the CNTs interact with cells and tissues. The standard method for this involves using transmission electron microscopy (TEM). However, in particular, the sample preparation, using a microtome to
F Wyss et al.
Veterinary pathology, 52(6), 1235-1242 (2015-01-27)
Pododermatitis is frequent in captive flamingos worldwide, but little is known about the associated histopathologic lesions. Involvement of a papillomavirus or herpesvirus has been suspected. Histopathologic evaluation and viral assessment of biopsies from 19 live and 10 dead captive greater
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico