01897

Adenosine 5′-diphosphate disodium salt

≥90%

• Sinónimos: ADPdisodium salt, Disodium 5′-ADP, Disodium adenosine 5′-diphosphate, 5′-ADP-Na₂
• Fórmula empírica (notación de Hill): C₁₀H₁₃N₅Na₂O₁₀P₂
• Número de CAS: 16178-48-6
• Peso molecular: 471.16
• Beilstein/REAXYS Number: 7563620
• EC Number: 240-314-7
• MDL number: MFCD00066635
• UNSPSC Code: 41106305
• eCl@ss: 32160414
• PubChem Substance ID: 329747370
• NACRES: NA.51

Propiedades

• Quality Level: 100
• assay: ≥90%
• form: powder or crystals
• optical activity: [α]20/D −29.6±1°, c = 0.5% in 0.5 M Na₂HPO₄
• impurities: ≤10% water
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChI key: ORKSTPSQHZNDSC-IDIVVRGQSA-L

Descripción

Application

Adenosine 5′-diphosphate disodium salt has been used as a purinergic G protein-coupled receptor P2Y12 agonistin platelet activation tests in blood samples.

Biochem/physiol Actions

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y₁ and P2Y₁₂. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)