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Merck

04231

Sigma-Aldrich

Calcium phosphate dibasic dihydrate

puriss., meets analytical specification of Ph. Eur., BP, USP, 98-102.5%

Sinónimos:

Calcium hydrogen phosphate dihydrate

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About This Item

Fórmula lineal:
CaHPO4 · 2H2O
Número de CAS:
Peso molecular:
172.09
EC Number:
MDL number:
UNSPSC Code:
51101500
PubChem Substance ID:
NACRES:
NA.21

grade

puriss.

Quality Level

assay

98-102.5%

form

powder

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

organic volatile impurities, complies
residual solvents, complies
≤0.003% heavy metals (as Pb)
≤0.1% insoluble in HCl

loss

24.5-26.5% loss on ignition, 800 °C

anion traces

carbonate (CO32-): in accordance
chloride (Cl-): ≤200 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤3000 mg/kg

cation traces

As: ≤1 mg/kg
Ba:, in accordance (Ph Eur)
Ba:, in accordance (USP)
Fe: ≤300 mg/kg

SMILES string

O.O.[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-2

InChI key

XAAHAAMILDNBPS-UHFFFAOYSA-L

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Application


  • Simultaneous Regulation of the Mechanical/Osteogenic Capacity of Brushite Calcium Phosphate Cement by Incorporating with Poly(ethylene glycol) Dicarboxylic Acid: This research investigates enhancing brushite calcium phosphate cements by adding poly(ethylene glycol) dicarboxylic acid to improve mechanical properties and osteogenic capabilities, applicable in bone regeneration and implant materials. (Gao et al., 2024).

  • Biosurfactant-Assisted Cu Doping of Brushite Coatings: Explores the structural and biofunctional enhancements of brushite coatings through copper doping facilitated by biosurfactants, which could revolutionize surface treatments for biocompatible implants and devices. (Siva Prasad et al., 2024).

  • Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair: This study highlights the application of calcium phosphate dibasic dihydrate in developing protective coatings on magnesium-based implants, significantly advancing orthopedic and dental implant technologies. (Wu et al., 2024).

  • Physiologically Engineered Porous Titanium/Brushite Scaffolds for Critical-Size Bone Defects: Details the design and fabrication of novel scaffolds for treating large bone defects, utilizing a combination of titanium and brushite, highlighting its potential in reconstructive surgery and regenerative medicine. (Abdulaziz et al., 2023).

  • Mechanochemical Synthesis of Cerium Chlorapatite from a Mixture of Cerium Chloride Heptahydrate, Dicalcium Phosphate Dihydrate, and Calcium Hydroxide for Biomedical Application: Focuses on the innovative production of cerium chlorapatite using dicalcium phosphate dihydrate, showcasing its potential in biomedical engineering, especially in drug delivery and tissue engineering. (Otsuka et al., 2024).

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Moreton, R. C.
Chemical & Pharmaceutical Bulletin, 868-870 (1996)
J M Lausier et al.
Journal of pharmaceutical sciences, 66(11), 1636-1637 (1977-11-01)
The aging of direct compression tablets made using dibasic calcium phosphate dihydrate as the tablet matrix was investigated over 16 weeks. The formula included 6% amaranth as a dye tracer. Two sets of stress storage conditions were used: 25 degrees
Simo-Pekka Simonaho et al.
International journal of pharmaceutics, 409(1-2), 104-110 (2011-03-02)
Ultrasound transmission measurements were performed to evaluate the tensile strength of tablets. Tablets consisting of one ingredient were compressed from dibasic calcium phosphate dehydrate, two grades of microcrystalline cellulose and two grades of lactose monohydrate powders. From each powder, tablets
P Tschoppe et al.
Archives of oral biology, 54(9), 810-816 (2009-07-15)
In this in vitro study the effects of various calcium and phosphate additions to a commercially available saliva substitute on remineralization of demineralised dentin were investigated. Bovine dentin specimens (n=70) were prepared. Before and after demineralisation (37 degrees C, pH
Daniel L Alge et al.
Journal of biomedical materials research. Part A, 100(7), 1792-1802 (2012-04-11)
Calcium phosphate cements have many desirable properties for bone tissue engineering, including osteoconductivity, resorbability, and amenability to rapid prototyping-based methods for scaffold fabrication. In this study, we show that dicalcium phosphate dihydrate (DCPD) cements, which are highly resorbable but also

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