SYNPLE-C001

Reagent-cartridge Suzuki Coupling

Synple

• Sinónimos: Synple 2
• MDL number: MFCD32903606
• UNSPSC Code: 12161503
• NACRES: NA.22

Propiedades

• SMILES string: [s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C
• InChI key: HVPZHRHEHKZOOJ-TYBLODHISA-N

Descripción

General description

Reagent-cartridge Suzuki Coupling is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the synthesis of biaryl scaffolds through a Suzuki-Miyaura cross-coupling. The cartridge contains all necessary reagents and catalysts for coupling the user aryl bromide and aryl boronic acid.

Scale: up to 0.8 mmol
Compatible substrates: aryl bromides, aryl boronic acids

Cartridge contents:

• Supported Pd catalyst, Cs₂CO₃, Celite (for cross-coupling reaction)
• Supported carbonate (for purification)
• Silica and HM-N (for purification)

Learn more about the Synple automated synthesis platform.

Explore all our boronic acids

Features and Benefits of Synple Platform

• Time savings – pre-installed protocols have been highly optimized, which obviates the need for the user’s own reaction development and optimization
• Easy to use – protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety – all chemicals are contained in the system, minimizing the user’s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system – simple installation
• Reaction temperatures from 25 °C – 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

Other Notes

An integrated console for capsule-based, automated organic synthesis

Legal Information

Product of Synple Chem AG

Información de seguridad

• pictograms: GHS08,GHS05
• signalword: Danger
• hcodes: H318,H361f,H372
• pcodes: P202 - P260 - P264 - P280 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Dam. 1 - Repr. 2 - STOT RE 1 Inhalation
• target_organs: Lungs
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3