SMB01383

PhIP

≥95% (HPLC)

• Sinónimos: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
• Fórmula empírica (notación de Hill): C₁₃H₁₂N₄
• Número de CAS: 105650-23-5
• Peso molecular: 224.26
• MDL number: MFCD00210745
• UNSPSC Code: 12352100
• NACRES: NA.28

Propiedades

• biological source: synthetic
• Quality Level: 200
• assay: ≥95% (HPLC)
• form: solid
• shipped in: 2-8°C
• storage temp.: 2-8°C
• SMILES string: NC1=NC2=NC=C(C3=CC=CC=C3)C=C2N1C

Descripción

General description

PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) is a dietary genotoxic carcinogen formed in heat processed meat and fish via the Maillard reaction. PhIP is a primary metabolite activated by CYP1A2 and N-acetyltransferase 1 or sulfotransferase to DNA reactive metabolite.

Biochem/physiol Actions

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H315,H319,H335,H351
• pcodes: P202 - P261 - P264 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable