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Merck
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Documentos clave

PHR1299

Supelco

Pamabrom

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Pamabrom, PAM

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About This Item

Número de CAS:
606-04-2
EC Number:
210-103-4
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to USP 1077708

API family

pamabrom

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

InChI

1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3

InChI key

ATOTUUBRFJHZQG-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pamabrom is a weak diuretic which is used as an analgesic and an antihistamine for symptomatic control of the premenstrual syndrome. It typically assists in the reduction of bloating associated with premenstrual syndrome.

Application

Pamabrom may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA0585 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Referencia del producto
Descripción
Precios

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Guillermo Di Girolamo et al.
Expert opinion on pharmacotherapy, 5(3), 561-570 (2004-03-12)
Primary dysmenorrhoea is the most frequent gynaecological condition, with a prevalence of 40 - 90% in women within the reproductive age. It is characterised by cyclic pelvic pain related to menstrual period, vomiting and headache. As prostaglandins and leukotrienes appear
Jil K Swanson et al.
Journal of drugs in dermatology : JDD, 5(3), 284-286 (2006-04-01)
Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. An urticarial eruption, with systemic complaints consistent with a serum sickness-like reaction, attributed to Pamabron is described. A review of the literature concerning Pamabron and dermatology is discussed.
S Nedorost et al.
Cleveland Clinic journal of medicine, 58(1), 33-34 (1991-01-01)
A young woman presented with recurrent skin lesions that were predominantly perioral. Fixed drug reaction was diagnosed based on her history of intermittent ingestion of Pamprin, a common menstrual symptom reliever, and characteristic erythematous, pigmented, edematous patches. After oral challenge
Development and Validation of Three Spectrophotometric Methods for Simultaneous Determination of Paracetamol and Pamabrom in Bulk and Pharmaceutical Formulation
Abdelaleem EA, et al.
Analytical Chemistry Letters, 6(1), 13-23 (2016)
Fixed drug eruptions and oral rechallenge.
K Kauppinen
Cleveland Clinic journal of medicine, 58(1), 64-65 (1991-01-01)
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