Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

BCR312

2-Nitro-7-methoxynaphtho[2,1-b]furan

BCR®, certified reference material

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C13H9NO4
Número de CAS:
75965-74-1
Peso molecular:
243.21
Beilstein/REAXYS Number:
5749492
MDL number:
MFCD01712342
UNSPSC Code:
41116107
PubChem Substance ID:
329773821
NACRES:
NA.24

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc2c(ccc3oc(cc23)[N+]([O-])=O)c1

InChI

1S/C13H9NO4/c1-17-9-3-4-10-8(6-9)2-5-12-11(10)7-13(18-12)14(15)16/h2-7H,1H3

InChI key

BRRIJZQYTOFDAF-UHFFFAOYSA-N

Analysis Note

For more information please see:
BCR312

Legal Information

BCR is a registered trademark of European Commission

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H341

Hazard Classifications

Muta. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

P Quillardet et al.
Mutation research, 358(1), 113-122 (1996-10-28)
The influence of the uvr-dependent excision repair system on the lethal action, mutagenic specificity, SOS induction and DNA adducts formation of 7-methoxy-2-nitronaphtho[2,1-b]furan (R7000), a potent genotoxic nitrofuran, were examined in Escherichia coli. Binding measurements of 3H-labelled R7000 to DNA indicated
L Cui et al.
Cancer letters, 76(2-3), 161-166 (1994-01-30)
Among the nitro-naphthofurans, 7-methoxy-2-nitro-naphtho[2,1-b]furan (R7000) has proved to be a very potent mutagen that causes sarcomas at the subcutaneous injection site and carcinomas in the forestomach after p.o. administration. In the present study, possible promoting activity for diethylnitrosamine (200 mg/kg
R J Salmon et al.
Cancer letters, 35(1), 59-64 (1987-04-01)
7-Methoxy-2-nitro-naphtho[2,1-b]furan (R 7000) and its methylated homolog in position 1 (R 7372) are among the most mutagenic agents presently known, as shown by the results obtained both in the Ames test and in the SOS Chromotest. Their carcinogenic effects were
H Strapélias et al.
Carcinogenesis, 9(11), 1987-1993 (1988-11-01)
The metabolism of 7-methoxy-2-nitro-naphtho[2,1-b]furan and the subsequent binding to DNA, under aerobic conditions, were investigated using liver microsomes of both untreated rats and rats pre-treated with 3-methylcholanthrene [3-MC]. The metabolites were analyzed by HPLC. The following compounds: 7-hydroxy-2-nitro-naphtho[2,1-b]-furan-6,9-dione; 6,7-dihydro-2-nitro-naphtho[2,1-b]furan; 7-hydroxy-2-nitro-naphtho[2,1-b]furan
[In vitro antibacterial activity of 7-methoxy-2-nitronaphto [2,1-b]furan (R 7000)].
A Amgar et al.
Annales pharmaceutiques francaises, 41(3), 283-285 (1983-01-01)
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico