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Key Documents

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96699

Supelco

Poli(etilenglicol)

analytical standard, for GPC, 40,000

Sinónimos:

PEG

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About This Item

Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24890339
NACRES:
NA.24

grade

analytical standard
for GPC

Quality Level

100

shelf life

limited shelf life, expiry date on the label

mol wt

Mn ~36500
Mp ~40000
Mw ~41500

technique(s)

gel permeation chromatography (GPC): suitable

Mw/Mn

~1.14

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene glycol) is a nontoxic and non-biodegradable polymer, which can find applications in drug delivery systems.

Application


  • Poly(ethylene glycol) in biomaterials synthesis: Research showcases the development of disulfide-cross-linked tetra-PEG gels, highlighting the utility of poly(ethylene glycol) in creating advanced biomaterials that are biocompatible and functional for various biomedical applications (Meng et al., 2024).

  • PEGylation reagents for drug delivery: PEG is employed in the formation of hybrid polymersomes for mRNA delivery, demonstrating its critical role in enhancing the stability and cellular uptake of therapeutic agents, thereby improving treatment efficacy and safety (Shin et al., 2024).

  • Polyethylene glycol for organic synthesis: PEG is used in solvent-free sample preparations for MALDI-TOF MS of polymer blends, facilitating cleaner and more environmentally friendly processes in polymer analysis and characterization (Dalgic and Weidner, 2024).

  • PEG reagents for protein modification: PEG-based block copolymers are synthesized for drug delivery applications, where PEGylation significantly increases the solubility and stability of therapeutic molecules, enhancing their pharmacological profiles (Parcero-Bouzas et al., 2024).

  • Poly(ethylene glycol) in biotechnology: PEG is integrated into bioplastic formulations to improve the crystallization, thermal, and mechanical properties of poly(L-lactide) bioplastics, underscoring its versatility and importance in developing sustainable materials (Pakkethati et al., 2024).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCK2549
BCCJ8195
BCCJ3863
BCCH5783
BCCH2633

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Pharmacokinetic and biodistribution properties of poly (ethylene glycol)-protein conjugates.
Caliceti P and Veronese MF
Advanced Drug Delivery Reviews, 55(10), 1261-1277 (2003)
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Knop K, et al.
Angewandte Chemie (International Edition in English), 49(36), 6288-6308 (2010)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
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