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861340

Sigma-Aldrich

Thionin acetate salt

certified by the Biological Stain Commission, Dye content ≥85 %

Sinónimos:

3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet

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About This Item

Fórmula empírica (notación de Hill):
C12H9N3S · C2H4O2
Número de CAS:
78338-22-4
Peso molecular:
287.34
Colour Index Number:
52000
Beilstein/REAXYS Number:
4345073
MDL number:
MFCD00081194
UNSPSC Code:
12171500
PubChem Substance ID:
24888537
NACRES:
NA.47

grade

certified by the Biological Stain Commission

Quality Level

200

form

powder

composition

Dye content, ≥85%

λmax

598 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1

InChI

1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1

InChI key

OWXBIRAFHWASMS-UHFFFAOYSA-M

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General description

Thionin is a diaminothiazine, metachromatic cationic dye.

Application

Thionin is widely used as a biological stain, especially in histology. It has been used in the Nissl stain for the labeling of neuronal cell bodies.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
MKCM9285
MKCL1525
MKCH8482
MKCC9348
MKBZ4683V

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Contribution of carbohydrate histochemistry to glycobiology.
Danguy A, et al.
Histology and Histopathology, 9, 155-155 (1994)
Cerebellar Purkinje cell neurodegeneration after cardiac arrest: effect of therapeutic hypothermia.
Paine MG, et al.
Resuscitation, 83, 1511-1511 (2012)
Jingman Han et al.
Biosensors & bioelectronics, 47, 243-247 (2013-04-16)
Here we report a one-step approach to synthesize graphene oxide-thionine-Au (GO-Thi-Au) nanocomposites using the synergistic effect of Thi and GO. Thi molecules adsorbed on the nanocomposites still kept the property of electroactive redox. Meanwhile, the resulting Au nanoparticles (AuNPs) of
Shujun Yu et al.
Biosensors & bioelectronics, 48, 224-229 (2013-05-22)
A highly sensitive label-free immunosensor for the detection of kanamycin had been developed using silver hybridized mesoporous ferroferric oxide nanoparticles (Ag@Fe₃O₄ NPs) and thionine mixed graphene sheet (TH-GS). TH was used as an electron transfer mediator. The electrical signal was
Wen Li et al.
Analytical chemistry, 84(17), 7583-7590 (2012-08-14)
Site-specific identification of DNA methylation and assay of MTase activity are important in determining specific cancer types, providing insights into the mechanism of gene repression, and developing novel drugs to treat methylation-related diseases. This work reports an electrochemical method for
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