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Merck

74595

Supelco

(±)-Glicidol

analytical standard

Sinónimos:

(±)-Oxiran-2-metanol, 2,3- epoxi-1-propanol, Glicerolglúcido

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About This Item

Fórmula empírica (notación de Hill):
C3H6O2
Número de CAS:
Peso molecular:
74.08
Beilstein/REAXYS Number:
383562
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

vapor density

2.15 (vs air)

vapor pressure

0.9 mmHg ( 25 °C)

assay

≥95.0% (GC)

autoignition temp.

780 °F

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.429-1.437
n20/D 1.433 (lit.)

bp

61-62 °C/15 mmHg (lit.)

density

1.117 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

OCC1CO1

InChI

1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2

InChI key

CTKINSOISVBQLD-UHFFFAOYSA-N

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General description

Glycidol is an aliphatic epoxide which may be used as a stabilizer in the manufacture of vinyl polymers, as an additive for oil and synthetic hydraulic fluids, and also as a diluent in some epoxy resins.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

161.6 °F

flash_point_c

72 °C


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Certificados de análisis (COA)

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Carcinogenicity of glycidol in F344 rats and B6C3F1 mice.
Irwin RD, et al.
Journal of Applied Toxicology, 16(3), 201-209 (1996)
NTP Toxicology and Carcinogenesis Studies of Glycidol (CAS No. 556-52-5) In F344/N Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program and others
National Toxicology Program Technical Report Series, 374(3), 1-1 (1990)
Glycidol.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 469-486 (2000-12-02)
Hirotoshi Akane et al.
Journal of applied toxicology : JAT, 34(12), 1389-1399 (2014-01-08)
We previously found that exposure to glycidol at 1000 ppm in drinking water caused axonopathy in maternal rats and aberrations in late-stage hippocampal neurogenesis, targeting the process of neurite extension in offspring. To identify the profile of developmental neurotoxicity of
Kunio Wada et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 769, 1-6 (2014-10-26)
The in vivo comet assay has been used for the evaluation of DNA damage and repair in various tissues of rodents. However, it can give false-positive results due to non-specific DNA damage associated with cell death. In this study, we

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