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Merck

68317

Supelco

Ginsenoside Rg1

analytical standard

Sinónimos:

(3β,6α,12β)-3,12-Dihydroxydammar-24-ene-6,20-diyl bis-β-D-glucopyranoside

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About This Item

Fórmula empírica (notación de Hill):
C42H72O14
Número de CAS:
Peso molecular:
801.01
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥90% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@](CCC=C(C)C)(C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])[C@H](C1)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1

InChI key

YURJSTAIMNSZAE-HHNZYBFYSA-N

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General description

Ginsenoside Rg1 is a major component of the root and stem of ginseng plant. It possesses a broad spectrum of pharmacological properties like neuroprotection, anti-inflammation, anti-aging, anti-fatigue and memory-enhancing properties.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This compound is commonly found in plants of the genus: panax

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Certificados de análisis (COA)

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Visite la Librería de documentos

Ginsenoside Rg1 protects against sepsis-associated encephalopathy through beclin 1?independent autophagy in mice
Li Y, et al.
The Journal of Surgical Research, 207, 181-189 (2017)
Neuroprotective Effect of the Ginsenoside Rg1 on Cerebral Ischemic Injury In Vivo and In Vitro Is Mediated by PPAR?-Regulated Antioxidative and Anti-Inflammatory Pathways
Li Y, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM (2017)
Wei Li et al.
Brain research bulletin, 88(5), 501-506 (2012-05-24)
Excessive accumulation of amyloid-β (Aβ) has been proposed as a pivotal event in Alzheimer's disease (AD) pathogenesis. Possible mechanisms underlying Aβ-induced neurotoxicity include inflammation and apoptosis. Here, the protective effect of ginsenoside Rg1 (GRg1) on neuronal damage was examined in
QianKun Quan et al.
PloS one, 8(3), e59155-e59155 (2013-03-23)
The present study was designed to examine the effects of ginsenoside Rg1 on expression of peroxisome proliferator-activated receptor γ (PPARγ) and insulin-degrading enzyme (IDE) in the hippocampus of rat model of Alzheimer's disease (AD) to determine how ginsenoside Rg1 (Rg1)
Wei Li et al.
Life sciences, 91(15-16), 809-815 (2012-09-18)
In the present study we aimed to investigate the neuroprotective effect of ginsenoside Rg1 (GRg1) on neuronal damage examined in an adopted in vitro inflammatory neurodegeneration model and the involvement of p38 MAPK signal pathway. The supernatant from Aβ(1-40)-stimulated THP-1

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