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Key Documents

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11569

Supelco

3,4-Dihydroxyphenylacetic acid

analytical standard

Sinónimos:

DOPAC, Homoprotocatechuic acid

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About This Item

Fórmula lineal:
(HO)2C6H3CH2CO2H
Número de CAS:
102-32-9
Peso molecular:
168.15
Beilstein/REAXYS Number:
2211017
EC Number:
203-024-1
MDL number:
MFCD00004338
UNSPSC Code:
77101502
PubChem Substance ID:
329749488
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥97.0% (HPLC)
97.0-103.0% (T)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

127-130 °C (lit.)

application(s)

pharmaceutical

format

neat

SMILES string

OC(=O)Cc1ccc(O)c(O)c1

InChI

1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)

InChI key

CFFZDZCDUFSOFZ-UHFFFAOYSA-N

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Application

3,4-Dihydroxyphenylacetic acid may be used as a reference standard for the determination of 3,4-dihydroxyphenylacetic acid in rat samples by high-performance liquid chromatography with electrochemical detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCG7067
BCCB9579
BCBW1684
BCBS4459V
BCBN1293V

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Simultaneous determination of 3, 4?dihydroxyphenylalanine, 5?hydroxytryptophan, dopamine, 4?hydroxy?3?methoxyphenylalanine, norepinephrine, 3, 4?dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5?hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high?performance liquid chromatography with electrochemical detection.
Wagner J, et al.
Journal of Neurochemistry, 38(5), 1241-1254 (1982)
Jinhee Kim et al.
Biomolecules & therapeutics, 28(3), 282-291 (2020-04-28)
Inhaled solvents such as toluene are of particular concern due to their abuse potential that is easily exposed to the environment. The inhalation of toluene causes various behavioral problems, but, the effect of short-term exposure of toluene on changes in
Wanqiu Huang et al.
Journal of neurochemistry, 150(3), 282-295 (2019-05-24)
Neuroinflammation is one of the driving forces of progressive neurodegeneration in Parkinson's disease (PD). The metabolomics approach has been proved highly useful in identifying potential therapeutic targets. Here, to identify inflammation-relevant treatment targets for PD, mass spectrometry-based untargeted metabolomics was
Sandy Stayte et al.
PloS one, 10(4), e0124325-e0124325 (2015-04-23)
Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by a significant loss of dopaminergic neurons within the substantia nigra pars compacta (SNpc) and a subsequent loss of dopamine (DA) within the striatum. Despite advances in the development of pharmacological
Bing Han et al.
Parkinsonism & related disorders, 20(11), 1191-1195 (2014-09-16)
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that is caused predominantly by the degeneration of the nigrostriatal dopaminergic pathway. Lateral habenula (LHb) has efferent projections that terminate in the substantia nigra pars compacta (SNpc) and electrical stimulation of
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