Saltar al contenido
Merck

03716

Supelco

(±)-Lisofylline

analytical standard

Sinónimos:

Lisofylline, (±)-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine, 5-Hydroxy pentoxifylline, Penthydroxyfylline

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Fórmula empírica (notación de Hill):
C13H20N4O3
Número de CAS:
Peso molecular:
280.32
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

O=C1N(CCCCC(O)C)C(N(C)C2=C1N(C)C=N2)=O

InChI

1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3

InChI key

NSMXQKNUPPXBRG-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

General description

Lisofylline (LSF) is a synthetically modified methylxanthine which is known to exhibit various therapeutic properties. It is a potent anti-inflammatory agent and an antioxidant with the ability to suppress oxygen radical production. LSF is used for treating acute lung injury and also has a role in the early treatment of diabetes.

Application

Lisofylline may be used as an analytical reference standard for the determination of the analyte in rat plasma by various high-performance liquid chromatography (HPLC) based techniques.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Lisofylline, a novel antiinflammatory agent, protects pancreatic $\beta$-cells from proinflammatory cytokine damage by promoting mitochondrial metabolism
Chen M, et al.
Endocrinology, 143(6), 2341-2348 (2002)
Combined treatment with lisofylline and exendin-4 reverses autoimmune diabetes
Yang Z, et al.
Biochemical and Biophysical Research Communications, 344(3), 1017-1022 (2006)
Lisofylline: a potential lead for the treatment of diabetes
Yang Z, et al.
Biochemical Pharmacology, 69(1), 1-5 (2005)
Simultaneous estimation of lisofylline and pentoxifylline in rat plasma by high performance liquid chromatography-photodiode array detector and its application to pharmacokinetics in rat
Italiya KS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1061(1), 49-56 (2017)
Validation of a high
Walczak M, et al.
Acta Poloniae Pharmaceutica, 66(3), 215-224 (2009)

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico