02150595

Osthole

primary reference standard

• Sinónimos: 7-Methoxy-8-(3-methyl-2-butenyl)coumarin, 7-Methoxy-8-isopentenylcoumarin, Osthol
• Fórmula empírica (notación de Hill): C₁₅H₁₆O₃
• Número de CAS: 484-12-8
• Peso molecular: 244.29
• MDL number: MFCD00076049
• UNSPSC Code: 85151701
• PubChem Substance ID: 329747396
• NACRES: NA.24

Propiedades

• grade: primary reference standard
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: HWI
• application(s): food and beverages
• SMILES string: COc1ccc2C=CC(=O)Oc2c1C\C=C(\C)C
• InChI: 1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
• InChI key: MBRLOUHOWLUMFF-UHFFFAOYSA-N

Descripción

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Biochem/physiol Actions

Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model. Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders. Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable