10982962001

N-Acetyl-β-D-Glucosaminidase Standard (NAG Standard)

from beef kidney

• Sinónimos: NAG standard
• UNSPSC Code: 12352204

Propiedades

• biological source: bovine kidney
• Quality Level: 100
• form: lyophilized
• specific activity: ~20 mU/mL
• packaging: pkg of 5 × 3 mL (5 x 400 μg)
• manufacturer/tradename: Roche
• technique(s): activity assay: suitable
• color: white to light yellow
• solubility: water: soluble
• application(s): life science and biopharma
• storage temp.: 20-25°C

Descripción

General description

Standard for the determination of NAG activity in urine research samples with the aid of the Test-Combination N-acetyl-β-D-glucosaminidase.
N-Acetyl-β-D-Glucosaminidase is a high molecular weight lysosomal enzyme existing as two isofomrs, Isoenzyme-A and Isoenzyme-B. It is present in human kidney. It has high molecular weight. It is highly active in renal proximal tubular cells. It has been reported that overexpressed urine-NAG reflects the proximal tubular dysfunction of the kidney.

Application

The NAG standard is used for the determination of NAG activity in urine in life science research applications, with the aid of N-acetyl-β-D-glucosaminidase. It can be used in automatic analyzers.

Unit Definition

Volume Activity: The activity of the NAG standard is approximately 20 mU N-acetyl-β-D-glucosaminidase from beef kidney per ml. For exact values, see data printed on the label.

Preparation Note

Storage conditions (working solution): 2 to 8 °C
Stability of the standard solution
The solution is stable for at least 1 month stored at 2 to 8 °C, protected from light.

Reconstitution

Preparation of the standard solution
Dissolve contents of one bottle with 3 ml double distilled water, close bottle and wait for 5 minutes. Dissolve contents completely by gentle swirling. Avoid creating foam.

Storage and Stability

Keep protected from light.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Información de seguridad

• hcodes: H412
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash