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Merck
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Key Documents

RKTX1MAG-37K

Millipore

MILLIPLEX® Rat Kidney Toxicity Magnetic Bead Panel 1 - Toxicity Multiplex Assay

The analytes available for this multiplex kit are: Clusterin, GSTα, IP-10, KIM-1, OPN - Osteopontin, TIMP-1, VEGF.

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Quality Level

200

species reactivity

rat

manufacturer/tradename

Milliplex®

assay range

accuracy: 70-123%
standard curve range: 0.03-20 ng/mL
(IP-10, KIM-1, OPN)
standard curve range: 0.03-20 ng/mL
(VEGF)
standard curve range: 0.27-200 ng/mL
(TIMP-1)
standard curve range: 2.06-1500 ng/mL
(Clusterin)
standard curve range: 4.12-3000 ng/mL
(GSTα)
inter-assay cv: <10%
intra-assay cv: <15%
(All other analytes)
inter-assay cv: <20%
intra-assay cv: <30%
(GSTα)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

shipped in

wet ice

General description

MILLIPLEX® Rat Kidney Toxicity Bead Panels 1 & 2, coupled with the Luminex® xMAP®platform in a bead format, enables you to focus on discovery so you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, dramatically improving productivity.

Panel Type: Toxicity

Application

  • Analytes: Clusterin GSTα IP-10 KIM-1 OPN - Osteopontin TIMP-1 VEGF
  • Recommended Sample type: urine
  • Recommended Sample dilution: 1:2
  • Assay Run Time: Overnight

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Other Notes

Sensitivity: See kit protocol for individual analytes sensitivities.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Javad Habibi et al.
Cardiovascular diabetology, 18(1), 40-40 (2019-03-27)
Diabetic nephropathy (DN) is characterized by glomerular and tubulointerstitial injury, proteinuria and remodeling. Here we examined whether the combination of an inhibitor of neprilysin (sacubitril), a natriuretic peptide-degrading enzyme, and an angiotensin II type 1 receptor blocker (valsartan), suppresses renal
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology Letters null
Iwan P Williams et al.
mAbs, 12(1), 1685349-1685349 (2019-11-27)
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and
Nadeeka S Udawatte et al.
Frontiers in pharmacology, 11, 511-511 (2020-05-12)
Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adverse
Klintean Wunnapuk et al.
Toxicology letters, 225(1), 192-200 (2013-12-24)
Accidental or intentional ingestion of glyphosate surfactant-based herbicides, like Roundup(®), leads to nephrotoxicity as well as death. In this study, a panel of kidney injury biomarkers was evaluated in terms of suitability to detect acute kidney injury and dysfunction. The

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