MABT61

Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302

clone R1.302.12, from mouse

• Sinónimos: poliovirus receptor-related 1 (herpesvirus entry mediator C), nectin-1, poliovirus receptor-related protein 1, poliovirus receptor-like 1, nectin 1, ectodermal dysplasia 4 (Margarita Island type), Herpesvirus entry mediator C, Herpes virus entry mediator
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: R1.302.12, monoclonal
• species reactivity: human
• technique(s): flow cytometry: suitable; immunofluorescence: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_002846
• UniProt accession no.: Q15223
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... PVRL1(5818)

Descripción

General description

Nectin-1, also known as poliovirus receptor-related protein 1 (PRR1 or PVRL1) or CD111, is an immunoglobulin-like transmembrane cell adhesion protein that also seems to play a role in neural tube formation, with N-cadherin. Nectins are known for being the receptors for the herpes simplex virus. Nectin-1 is connected with the actin cytoskeleton through afadin inside the cell. It is predominantly found in human placenta although in mice, expression is wide-ranging. Nectin-1 seems to adhere primarily to cells expressing nectin-4 and vice versa.

Immunogen

Human CD111 transfected NIH/3T3 cells

Application

Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Cocchi, F., et al. (1998). Journal of Virology. 72(12):9992–10002).

This Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302 is validated for use in FC, IF for the detection of Nectin-1/PVRL1 (CD111).

Quality

Evaluated by Flow Cytometry in human TF-1 cells.

Flow Cytometry Analysis: 0.25 µg of this antibody detected Nectin-1/PVRL1 in human TF-1 cells.

Target description

57 kDa calculated

Physical form

Format: Purified

Analysis Note

Control
Human TF-1 cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable