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Merck
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Key Documents

MAB5566

Sigma-Aldrich

Anti-Tubulin α Antibody, detyrosinated

ascites fluid, Chemicon®

Sinónimos:

Anti-Anti-B-ALPHA-1, Anti-Anti-LIS3, Anti-Anti-TUBA3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TUBA1A(7846)

Specificity

Alpha tubulin, detyrosinated.

Immunogen

Epitope: detyrosinated
Synthetic peptide GEEEGE.

Application

(add note)
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Neuronal & Glial Markers
This Anti-Tubulin Antibody, α, detyrosinated is validated for use in WB for the detection of Tubulin.

Physical form

Liquid. Contains no preservative.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Man to trypanosome: the tubulin tyrosination/detyrosination cycle revisited.
H T Idriss
Cell motility and the cytoskeleton, 45(3), 173-184 (2000-03-08)
A Mialhe et al.
Cancer research, 61(13), 5024-5027 (2001-06-30)
Tubulin, the dimeric subunit of microtubules, is a major cell protein that is centrally involved in cell division. Tubulin is subject to specific enzymatic posttranslational modifications including cyclic tyrosine removal and addition at the COOH terminus of the alpha-subunit. Tubulin
Low-intensity pulsed ultrasound accelerates tooth movement via activation of the BMP-2 signaling pathway.
Xue, H; Zheng, J; Cui, Z; Bai, X; Li, G; Zhang, C; He, S; Li, W; Lajud, SA; Duan, Y; Zhou, H
Testing null
Young-A Lee et al.
The European journal of neuroscience, 34(3), 426-436 (2011-06-23)
Chronic stress causes various detrimental effects including cognitive and affective dysfunctions. Given the recent findings emphasizing the importance of information processing between the prefrontal cortex (PFC) and limbic structures on cognitive and affective functions, impairments of these functions caused by
Fan Zhang et al.
Translational neurodegeneration, 4, 9-9 (2015-06-02)
In Alzheimer disease (AD), hyperphosphorylation of tau proteins results in microtubule destabilization and cytoskeletal abnormalities. Our prior ultra-morphometric studies documented a clear reduction in microtubules in pyramidal neurons in AD compared to controls, however, this reduction did not coincide with

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