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Key Documents

MAB1962Z

Sigma-Aldrich

Anti-Integrin β2 Antibody, clone P4H9, azide free

clone P4H9, Chemicon®, from mouse

Sinónimos:

CD18, MAB1962

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

P4H9, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG3

NCBI accession no.

NM_000211.2

UniProt accession no.

P05107

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB2(3689)

Specificity

beta2 integrin on hematopoeitic cells. Not present on platelets, endothelial cells, epithelial cells or fibroblasts.

Application

Anti-Integrin β2 Antibody, clone P4H9, azide free detects level of Integrin β2 & has been published & validated for use in IH.
Research Category
Cell Structure
Research Sub Category
Integrins
Suitable for use in immunofluorescence.

Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.

For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.

Physical form

Format: Purified
Sterile-filtered liquid containing no preservatives.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hee Doo Lee et al.
European journal of immunology, 44(4), 1156-1169 (2013-12-18)
Integrin trafficking, including internalization, recycling, and lysosomal degradation, is crucial for the regulation of cellular functions. Exosomes, nano-sized extracellular vesicles, are believed to play important roles in intercellular communications. This study demonstrates that exosomes released from human macrophages negatively regulate
Vira V Artym et al.
The Journal of cell biology, 208(3), 331-350 (2015-02-04)
Cell interactions with the extracellular matrix (ECM) can regulate multiple cellular activities and the matrix itself in dynamic, bidirectional processes. One such process is local proteolytic modification of the ECM. Invadopodia of tumor cells are actin-rich proteolytic protrusions that locally

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