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Key Documents

MAB1056

Sigma-Aldrich

Anti-Neutrophil Elastase Antibody, clone AHN-10

ascites fluid, clone AHN-10, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

AHN-10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SERP1(27230)

Specificity

Reacts specifically with human neutrophil elastase and not with the 3 homologous neutrophil neutral serine proteases, cathepsin G, esterase N and proteinase 3. Inhibits the elastinolytic activity of elastase. Elastase is felt to play an important role in a number of disease states.

Application

Anti-Neutrophil Elastase Antibody, clone AHN-10 detects level of Neutrophil Elastase & has been published & validated for use in IP, RIA & IC.
Immunoprecipitation

Immunocytochemistry

RIA

Optimal working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms

Storage and Stability

Maintain in convenient aliquots at -20°C or colder for up to 12 months. Avoid thawing and refreezing.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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K M Skubitz et al.
Journal of leukocyte biology, 44(3), 158-165 (1988-09-01)
Neutrophil proteases are believed to play a role in the pathogenesis of a variety of human diseases. While many studies of proteases in models of disease have focused on elastase, neutrophils contain several proteases some of which share a high

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