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HNDG3MAG-36K

Millipore

MILLIPLEX® Human Neurodegenerative Disease Magnetic Bead Panel 3 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: BDNF, Cathepsin D, MPO, NCAM, PAI-1 (total), PDGF-AA, PDGF-AB/BB, RANTES, sICAM-1, sVCAM-1.

Sinónimos:

Human NeuroscienceProtein MultiplexAssay, Luminex® Human Neuroscience Panel, Millipore Human Neuroscience Immunoassay

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Quality Level

species reactivity

human

manufacturer/tradename

Milliplex®

assay range

accuracy: 108%
(RANTES)

accuracy: 108%
(sICAM-1)

accuracy: 111%
(Cathepsin D)

accuracy: 123%
(PDGF-AA)

accuracy: 137%
(PDGF-AB/BB)

standard curve range: 2-10,000 pg/mL
(RANTES)

standard curve range: 2.4-10,000 pg/mL
(BDNF)

standard curve range: 2.4-10,000 pg/mL
(PAI-1 (total))

standard curve range: 2.4-10,000 pg/mL
(PDGF-AA)

standard curve range: 24-100,000 pg/mL
(Cathepsin D)

standard curve range: 24-100,000 pg/mL
(MPO)

standard curve range: 24-100,000 pg/mL
(NCAM)

standard curve range: 24-100,000 pg/mL
(PDGF-AB/BB)

standard curve range: 24-100,000 pg/mL
(sICAM-1)

standard curve range: 61-250,000 pg/mL
(sVCAM-1)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

shipped in

wet ice

General description

The MILLIPLEX® Human Neurodegenerative Bead Panel 3 (HNDG3MAG-36K) is to be used for the simultaneous quantification of the following 10 analytes in any combination: BDNF, Cathepsin D, MPO, NCAM, PAI-1 (total), PDGF-AA, PDGF-AB/BB, RANTES, sICAM-1, and sVCAM-1. This kit may be used for the analysis of all above analytes in human serum, plasma, and cerebrospinal fluid samples.

Panel Type: Neuroscience

Specificity

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Application

  • Analytes: BDNF, Cathepsin D, MPO, NCAM, PAI-1 (total), PDGF-AA, PDGF-AB/BB, RANTES, sICAM-1, sVCAM-1
  • Recommended Sample type: Serum, plasma, or CSF
  • Recommended Sample dilution: 1:100 diluted serum/plasma or neat CSF
  • Assay Run Time: Overnight
  • Research Category: Neuroscience
  • Research Subcategory: Category Alzheimer′s Disease Nervous System Neurodegenerative Diseases

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Packaging

Everything you need in a single kit.

Storage and Stability

Recommended storage for kit components is 2 - 8°C.

Other Notes

Sensitivity: See kit protocol for individual sensitvities

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids


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Rodrigo B Mansur et al.
Bipolar disorders, 18(5), 433-439 (2016-08-05)
Accumulating evidence indicates that oxidative stress and neurotrophins have a bidirectional relationship. In this post hoc, exploratory analysis, we investigated the association between plasma brain-derived neurotrophic factor (BDNF) levels and activities of the antioxidant enzymes glutathione peroxidase (GPx) and superoxide
Rong Ma et al.
OncoTargets and therapy, 13, 1883-1892 (2020-03-19)
This study aimed to investigate the diagnosis and prediction of serum platelet-derived growth factor (PDGF) level in patients with lung cancer (LC). Serum concentrations of PDGF-AA and PDGF-AB/BB were determined via Luminex assay in 210 patients with non-small cell lung
Luís F Martins et al.
Scientific reports, 7(1), 4153-4153 (2017-06-25)
Mesenchymal stem cells (MSCs) have been used for cell-based therapies in regenerative medicine, with increasing importance in central and peripheral nervous system repair. However, MSCs grafting present disadvantages, such as, a high number of cells required for transplantation and low
Kiyokazu Atake et al.
Frontiers in psychiatry, 9, 232-232 (2018-06-14)
Background: Cognitive impairment in schizophrenia can result in considerable difficulty in performing functions of daily life or social rehabilitation. Cognitive impairment in schizophrenia is related to various factors, such as the psychotic severity, aging, medication, and brain-derived neurotrophic factor (BDNF).
Nicole Ziliotto et al.
Thrombosis research, 191, 113-124 (2020-05-22)
Venous bed specificity could contribute to differential vulnerability to thrombus formation, and is potentially reflected in mRNA profiles. Microarray-based transcriptome analysis in wall and valve specimens from internal jugular (IJV) and saphenous (SV) veins collected during IJV surgical reconstruction in

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