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Merck
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AB9916

Sigma-Aldrich

Anti-CYP2b10 Antibody

serum, Chemicon®

Sinónimos:

Cytochrome P450 2b10

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Cyp2B10(13088)

General description

CYP2b10 (Cytochrome P450, family 2, subfamily b, polypeptide 10) is a member of the cytochrome P450 superfamily of monooxygenase enzymes which catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids.

Specificity

AB9916 is specific for CYP2b10.

Immunogen

Epitope: AA I182 – T205
Recombinant 2b10

Application

This Anti-CYP2b10 Antibody is validated for use in WB for the detection of CYP2b10.

Quality

Routinely evaluated by immunoblot.

Target description

58kDa

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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Shinhee Park et al.
Acta pharmaceutica Sinica. B, 6(5), 475-491 (2016-10-07)
Intestine is responsible for the biotransformation of many orally-exposed chemicals. The constitutive androstane receptor (CAR/Nr1i3) is known to up-regulate many genes encoding drug-metabolizing enzymes and transporters (drug-processing genes/DPGs) in liver, but less is known regarding its effect in intestine. Sixty-day-old
Kentaro Nobutani et al.
Pharmacology research & perspectives, 5(5) (2017-10-04)
Herbal medicines and natural products used for maintenance of health or treatment of diseases have many biological effects, including altering the pharmacokinetics and metabolism of other medications. Daikenchuto (TU-100), an aqueous extract of ginger, ginseng, and Japanese green pepper fruit
Cindy Yanfei Li et al.
Toxicological sciences : an official journal of the Society of Toxicology, 153(2), 282-302 (2016-07-15)
Safety concerns have emerged regarding the potential long-lasting effects due to developmental exposure to xenobiotics. The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are critical xenobiotic-sensing nuclear receptors that are highly expressed in liver. The goal of this
Xia Wen et al.
The Journal of pharmacology and experimental therapeutics, 344(1), 244-252 (2012-10-12)
Phase II enzymes, including Ugts, Sults, and Gsts, are critical for the disposition and detoxification of endo- and xenobiotics. In this study, the mRNA and protein expression of major phase II enzymes, as well as key regulatory transcription factors, were
Pan Chen et al.
British journal of pharmacology, 174(23), 4345-4361 (2017-09-15)
The tumour suppressor p53 is traditionally recognized as a surveillance molecule to preserve genome integrity. Recent studies have demonstrated that it contributes to metabolic diseases. Here, we investigated the role of p53 in the regulation of bile acid disposition and

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