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Key Documents

AB2910

Sigma-Aldrich

Anti-Mcl-1 Antibody

serum, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_021960.3
NM_182763.1

UniProt accession no.

Q07820

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... MCL1(4170)

Specificity

Recognizes Human Mcl-1. Not reactive with other members of the Bcl-2 family, as verified by immunoblot.

Immunogen

Synthetic peptide corresponding to amino acids 121-139 of human Mcl-1.

Application

Immunoblot 1:2,000

Immunoprecipitation. Precipitates a 37-39 kDa protein, which appears as a doublet in some cells.

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

The following tissues/cells can serve as positive controls: tonsil, tonsillar B cells, B-cell lines Reh, Daudi, and Karpas 422.

Optimal working dilutions for AB2910 must be determined by end user.
Research Category
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
This Anti-Mcl-1 Antibody is validated for use in IP, WB, IH(P) for the detection of Mcl-1.

Physical form

Liquid antiserum.

Storage and Stability

Store at -20°C for up to 12 months in undiluted aliquots. Avoid repeated freeze-thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Descripción
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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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