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Key Documents

650357

Sigma-Aldrich

Trypsin Inhibitor, Soybean, High Activity

Trypsin Inhibitor, Soybean, High Activity, CAS 9035-81-8 is of the several protease inhibitors in soybeans. Inhibits trypsin in 1:1 stoichiometry.

Sinónimos:

Trypsin Inhibitor, Soybean, High Activity

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About This Item

Número de CAS:
9035-81-8
UNSPSC Code:
12352202
NACRES:
NA.28

Quality Level

300

assay

≥90% (SDS-PAGE)

form

lyophilized solid

specific activity

≥7,000 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated

color

white

solubility

67 mM potassium phosphate buffer, pH 7.6: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

Component VI of Rackis. Does not inhibit chymotrypsin activity.
Inactivates trypsin on an equal molar basis. To ensure complete inhibition of trypsin activity, a working concentration of soybean trypsin inhibitor should exceed that of trypsin by a factor of at least 2.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Trypsin
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of protein that will inhibit 1 unit of trypsin activity using BAEE as a substrate at 25°C, pH 7.6.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Uchino, T., et al. 1993. J. Biol. Chem.268, 527.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

10-13 - German Storage Class 10 to 13

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Pancreatitis is characterized by acinar cell death and persistent inflammation. Ferroptosis is a type of lipid peroxidation-dependent necrosis, which is negatively regulated by glutathione peroxidase 4. We studied how trypsin, a serine protease secreted by pancreatic acinar cells, affects the

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