523350

PTIO

Nitric oxide radical scavenger.

• Sinónimos: PTIO, 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide
• Fórmula empírica (notación de Hill): C₁₃H₁₇N₂O₂
• Número de CAS: 18390-00-6
• Peso molecular: 233.29
• MDL number: MFCD00059929
• UNSPSC Code: 12352200

Propiedades

• Quality Level: 100
• assay: ≥98% (titration)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: dark blue
• solubility: ethanol: soluble; water: soluble
• shipped in: ambient
• storage temp.: −20°C
• InChI: 1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
• InChI key: DYUUGILMVYJEHY-UHFFFAOYSA-N

Descripción

General description

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.

Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner, without affecting nitric oxide synthase activity. Inhibits enhanced vascular permeability in solid tumors.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Nitric oxide radical scavenger

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.

Other Notes

Hogg, N., et al. 1995. Free Radic. Res. 22, 47.
Maeda, H., et al. 1994. Jpn. J. Cancer Res.85, 331.
Yoshida, M., et al. 1994. Biochem. Biophys. Res. Commun.202, 923.
Akaike, T., et al. 1993. Biochemistry32, 827.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable