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Key Documents

407317

Sigma-Aldrich

Anti-Integrin β₆ Mouse mAb (442.5C4)

liquid, clone 442.5C4, Calbiochem®

Sinónimos:

Integrin β₆ Detection Antibody, Mouse Anti-Integrin β₆

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

442.5C4, monoclonal

form

liquid

does not contain

preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ITGB6(3694)

General description

Mouse monoclonal antibody supplied as undiluted ascites. Recognizes the β6 integrin chain.
Recognizes the β6 integrin chain.
This Anti-Integrin β₆ Mouse mAb (442.5C4) is validated for use in ELISA, FC, Immunoblotting, IP, Paraffin Sections for the detection of Integrin β₆.

Immunogen

Human
recombinant, human αvβ₆

Application

ELISA (see comments)

Flow Cytometry (1:50-1:100)

Immunoblotting (1:50-1:100)

Immunoprecipitation (1:50-1:100)

Paraffin Sections (1:50-1:100)

Warning

Toxicity: Standard Handling (A)

Physical form

Undiluted ascites.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Miller, L.A., et al. 2001. J. Histochem. Cytochem.49, 41.
Breuss, J.M., et al. 1995. J. Cell Sci.108, 2241.
Hynes, R.O. 1992. Cell.69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell.45, 549.
This antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Expression of the cellular transmembrane receptor αvβ6 integrin is essentially restricted to malignant epithelial cells in carcinomas of a broad variety of lineages, whereas it is virtually absent in normal adult tissues. Thus, it is a highly attractive target for

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