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Merck
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Key Documents

16-107

Sigma-Aldrich

Anti-PI3 Kinase Antibody, p85 Protein, agarose conjugate, 200 µg

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable

NCBI accession no.

NM_181504.2
NM_181523.1
NM_181524.1

UniProt accession no.

P27986

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PIK3R1(5295)

General description

Anti-PI 3-Kinase antibody (06-195) covalently coupled to protein A-agarose by dimethyl-pimelimidate.

Application

Anti-PI3 Kinase Antibody, p85, agarose conjugate detects level of PI3 Kinase & has been published & validated for use in IP.

Features and Benefits

Format: Gel Immobilized

Quality

routinely evaluated by immunoprecipitating PI 3-Kinase from RIPA lysate of EGF-stimulated human A431 carcinoma cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.
Rabinovsky, R; Pochanard, P; McNear, C; Brachmann, SM; Duke-Cohan, JS; Garraway, LA; Sellers, WR
Molecular and cellular biology null
Timothy J Thauland et al.
Frontiers in immunology, 10, 753-753 (2019-04-30)
Gain-of-function variants in p110δ, the catalytic subunit of phosphatidylinositol 3-kinase (PI3K) expressed in lymphocytes, cause activated PI3-kinase δ syndrome (APDS), a primary immunodeficiency that is characterized by recurrent infections, viremia, lymphadenopathy, and autoimmunity. The mechanism of autoimmunity in APDS has
Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle.
McCurdy, CE; Davidson, RT; Cartee, GD
American Journal of Physiology. Endocrinology and Metabolism null

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