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Merck
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Key Documents

05-164

Sigma-Aldrich

Anti-PLCβ-1 Antibody

Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

rat, mouse, bovine, human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PLCB1(23236)

Specificity

PLCβ-1, also recognize the 100kDa and 41kDa fragments of PLCβ-1.1

Immunogen

Mixed monoclonal antibodies raised against purified bovine PLCβ-1

Application

Detect PLCβ-1 using this Anti-PLCβ-1 Antibody validated for use in IP.
Research Category
Signaling
Research Sub Category
Lipid Signaling

Quality

routinely evaluated by immunoprecipition of PLCβ-1 from a bovine brain membrane preparation, subsequent immunoblotting performed by the antibody

Target description

150 kDa

Physical form

100mM Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
Format: Purified
Protein G Chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Changes in sarcolemmal PLC isoenzymes in postinfarct congestive heart failure: partial correction by imidapril.
P S Tappia, S Y Liu, S Shatadal, N Takeda, N S Dhalla, V Panagia
The American Journal of Physiology null
Phospholipase C-beta1 is present in the botrysome, an intermediate compartment-like organelle, and Is regulated by visual experience in cat visual cortex
Kind, P. C., et al
The Journal of Neuroscience, 17, 1471-1480 (1997)
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.
Christmann, M; Tomicic, MT; Aasland, D; Berdelle, N; Kaina, B
Nucleic Acids Research null
P Sánchez-Blázquez et al.
The Journal of pharmacology and experimental therapeutics, 285(2), 820-827 (1998-05-15)
To analyze the selectivity of delta receptor subtypes to regulate different classes of G proteins, the expression of the alpha-subunits of Gi2, Gi3, Go1, Go2, Gq and G11 transducer proteins was reduced by administration of oligodeoxynucleotides (ODNs) complementary to sequences
Roberta Fiume et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(3), 957-966 (2008-11-26)
Inositide-specific phospholipase Cbeta1 (PLCbeta1) signaling in cell proliferation has been investigated thoroughly in the G(1) cell cycle phase. However, little is known about its involvement in G(2)/M progression. We used murine erythroleukemia cells to investigate the role of PLCbeta1 in

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