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Merck

N-920

Supelco

Norbuprenorphine-D3 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

Norbuprenorphine-d3

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About This Item

Fórmula empírica (notación de Hill):
C25H32D3NO4
Número de CAS:
Peso molecular:
416.57
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

[2H]C([2H])([2H])O[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6O[C@@H]2[C@]3(CCN4)c56

InChI

1S/C25H35NO4/c1-21(2,3)22(4,28)16-13-23-8-9-25(16,29-5)20-24(23)10-11-26-17(23)12-14-6-7-15(27)19(30-20)18(14)24/h6-7,16-17,20,26-28H,8-13H2,1-5H3/t16-,17-,20-,22+,23-,24+,25-/m1/s1/i5D3

InChI key

YOYLLRBMGQRFTN-QLWKBOQPSA-N

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General description

Norbuprenorphine is the primary active metabolite of the opiate buprenorphine in urine. This internal standard is suitable for quantitation of norbuprenorphine levels or isotope dilution methods by GC/MS or LC/MS for pain prescription monitoring, clinical toxicology, urine drug testing or forensic analysis. Buprenorphine, sold under trade names such as Buprenex®, Subutex® and Suboxone®, is an opiate drug used to treat opioid addiction and moderate to acute pain.

Application

  • Improving GC-MS Analysis of Norbuprenorphine: A study by Gervais JR and Hobbs GA discusses the use of an acetyl derivative to enhance the GC-MS analysis of Norbuprenorphine in urine, particularly in the presence of high concentrations of Buprenorphine, highlighting its significance as an analytical standard in forensic and clinical toxicology (Gervais and Hobbs, 2016).
  • Quantification of Acetaminophen Protein Adducts: Cook SF et al. developed a method for the quantification of a biomarker for acetaminophen protein adducts in human serum using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. This study demonstrates the application of advanced analytical techniques in toxicology and pharmacokinetics, where Norbuprenorphine-D3 serves as a reliable internal standard (Cook et al., 2015).

Legal Information

Buprenex is a registered trademark of Reckitt & Colman (Overseas) Ltd
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Suboxone is a registered trademark of RB Pharmaceuticals Limited
Subutex is a registered trademark of RB Pharmaceuticals Limited

Related product

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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