L-027

Lacosamide-¹³C, D₃ solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): ¹³CC₁₂D₃H₁₅N₂O₃
• Peso molecular: 254.30
• EC Number: 200-835-2
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in acetonitrile
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: [2H][13C]([2H])([2H])OC[C@@H](NC(C)=O)C(=O)NCc1ccccc1
• InChI: 1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1/i2+1D3
• InChI key: VPPJLAIAVCUEMN-RUXIMPAMSA-N

Descripción

General description

Lacosamide is a new antiepileptic drug approved by the FDA in late 2008 for the treatment of partial-onset seizures and diabetic neuropathic pain. The drug is marketed under the trade name Vimpat^®. This internal standard is suitable for lacosamide testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing.

Application

• Lacosamide-¹³C,D₃ in Pharmacokinetic Research: A study employed Lacosamide-¹³C,D₃ in a selective quantification method using UPLC-MS/MS, focusing on its pharmacokinetic profiles in healthy subjects. This research underscores the utility of stable isotope-labeled Lacosamide in assessing drug metabolism and distribution, crucial for optimizing therapeutic dosages and improving drug safety profiles (Bharwad et al., 2020).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Vimpat is a registered trademark of Harris FRC Corporation

Información de seguridad

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302 + H312 + H332,H319
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 35.6 °F - closed cup
• flash_point_c: 2 °C - closed cup